Gene description for MYOC
Gene name myocilin
Gene symbol MYOC
Other names/aliases GLC1A
GPOA
JOAG
JOAG1
TIGR
Species Homo sapiens
 Experiment description of studies that identified MYOC in Aqueous humor

1
Experiment ID120
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 21362503   
OrganismHomo sapiens
Experiment descriptionProtein profile of exosomes from trabecular meshwork cells.
AuthorsStamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL.
Journal name JOP
Publication year2011
SampleAqueous humor
Sample nameAqueous humor - Normal
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV110011: EV-METRIC:33%, 33%, 56%

2
Experiment ID1258
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24400796   
OrganismHomo sapiens
Experiment descriptionExosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.
AuthorsKang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H.
Journal name J Proteome Res.
Publication year2014
SampleAqueous humor
Sample nameAge-related macular degeneration patients
Isolation/purification methodsExoQuick
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140174: EV-METRIC:13%, 13%

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